Ronald de Wit Selected Research

Prostatic Neoplasms (Prostate Cancer)

3/2024	Darolutamide does not interfere with OATP-mediated uptake of docetaxel.
12/2023	A common germline variant in CYP11B1 is associated with adverse clinical outcome of treatment with abiraterone or enzalutamide.
12/2023	Flow-based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product.
11/2023	Darolutamide Added to Docetaxel Augments Antitumor Effect in Models of Prostate Cancer through Cell Cycle Arrest at the G1-S Transition.
10/2023	68Ga-PSMA PET/CT for Response Evaluation of 223Ra Treatment in Metastatic Prostate Cancer.
6/2023	Validation of an LC-MS/MS method for simultaneous quantification of abiraterone, enzalutamide and darolutamide in human plasma.
4/2023	Effect of docetaxel added to bicalutamide in Hormone-Naïve non-metastatic prostate cancer with rising PSA, a randomized clinical trial (SPCG-14).
3/2023	A Compendium of AR Splice Variants in Metastatic Castration-Resistant Prostate Cancer.
1/2023	Real-world evidence of patients with metastatic castration-resistant prostate cancer treated with cabazitaxel: comparison with the randomized clinical study CARD.
1/2023	mFast-SeqS-based aneuploidy score in circulating cell-free DNA is a prognostic biomarker in prostate cancer.

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Ronald de Wit Research Topics

Disease

93	Prostatic Neoplasms (Prostate Cancer) 03/2024 - 10/2004
50	Neoplasms (Cancer) 02/2024 - 04/2003
19	Pain (Aches) 01/2022 - 10/2004
16	Carcinoma (Carcinomatosis) 09/2023 - 08/2005
9	Disease Progression 12/2023 - 11/2007
8	Testicular Neoplasms (Testicular Cancer) 12/2023 - 03/2003
8	Circulating Neoplastic Cells 01/2023 - 12/2015
7	Neutropenia 11/2023 - 01/2013
7	Neoplasm Metastasis (Metastasis) 10/2023 - 11/2007
6	Urinary Bladder Neoplasms (Bladder Cancer) 05/2024 - 02/2003
6	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 10/2021 - 10/2007
5	Fatigue 11/2017 - 09/2012
5	Vomiting 03/2015 - 11/2003
5	Nausea 03/2015 - 11/2003
4	Seminoma 10/2021 - 12/2006
3	Non-Muscle Invasive Bladder Neoplasms 05/2024 - 01/2021
3	Aneuploidy (Aneuploid) 01/2023 - 01/2022
3	Diarrhea 10/2021 - 09/2012
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2010 - 10/2007
2	Carcinoma in Situ 05/2024 - 01/2021
2	Colorectal Neoplasms (Colorectal Cancer) 12/2023 - 02/2021
2	Infections 11/2023 - 04/2023
2	Asthenia 10/2021 - 04/2015
2	Febrile Neutropenia 01/2020 - 04/2015
2	Urologic Neoplasms (Urological Cancer) 03/2018 - 01/2017
2	Pulmonary Embolism 04/2015 - 03/2015
2	Seizures (Absence Seizure) 01/2015 - 09/2012
2	Hodgkin Disease (Hodgkin's Disease) 01/2010 - 12/2009
1	Fever (Fevers) 04/2023
1	Bone Diseases (Bone Disease) 01/2023
1	Spontaneous Fractures (Pathological Fracture) 01/2022
1	Lymphopenia (Lymphocytopenia) 01/2022
1	Spinal Cord Compression 01/2022

Drug/Important Bio-Agent (IBA)

43	Docetaxel (Taxotere)FDA Link 03/2024 - 10/2004
27	cabazitaxel FDA Link 11/2023 - 03/2015
21	Androgen Receptors (Androgen Receptor)IBA 03/2024 - 09/2012
18	enzalutamideIBA 12/2023 - 09/2012
18	Cisplatin (Platino)FDA LinkGeneric 10/2021 - 03/2003
17	Prednisone (Sone)FDA LinkGeneric 04/2023 - 10/2004
16	pembrolizumabIBA 05/2024 - 01/2017
16	AndrogensIBA 12/2023 - 03/2005
16	Prostate-Specific Antigen (Semenogelase)IBA 04/2023 - 10/2004
15	abirateroneIBA 12/2023 - 03/2015
15	PlatinumIBA 12/2023 - 07/2016
11	Biomarkers (Surrogate Marker)IBA 03/2024 - 05/2008
10	Hormones (Hormone)IBA 04/2023 - 10/2004
6	taxaneIBA 11/2023 - 06/2014
6	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2014 - 10/2004
5	Immune Checkpoint InhibitorsIBA 02/2024 - 01/2017
5	Taxoids (Taxanes)IBA 11/2023 - 06/2014
5	Alkaline PhosphataseIBA 01/2023 - 11/2007
5	Cell-Free Nucleic AcidsIBA 01/2023 - 01/2018
5	RamucirumabIBA 01/2022 - 11/2017
4	Etoposide (VP 16)FDA LinkGeneric 10/2021 - 03/2003
4	Abiraterone AcetateIBA 01/2021 - 03/2015
4	Carboplatin (JM8)FDA LinkGeneric 01/2018 - 12/2006
4	Gemcitabine FDA Link 04/2012 - 02/2003
3	darolutamideIBA 03/2024 - 06/2023
3	B7-H1 AntigenIBA 01/2022 - 10/2020
3	apalutamideIBA 04/2021 - 01/2018
3	Methotrexate (Mexate)FDA LinkGeneric 01/2012 - 04/2003
3	Vinblastine (Vinblastine Sulfate)FDA Link 01/2012 - 04/2003
3	Aprepitant (Emend)FDA Link 02/2007 - 11/2003
3	AntiemeticsIBA 02/2007 - 08/2005
2	gallium 68 PSMA-11IBA 10/2023 - 11/2020
2	bicalutamide (Casodex)FDA LinkGeneric 04/2023 - 10/2013
2	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 01/2022
2	Circulating Tumor DNAIBA 01/2023 - 01/2017
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	Testosterone (Sustanon)FDA Link 12/2020 - 01/2018
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 11/2020 - 04/2003
2	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2020 - 11/2017
2	Messenger RNA (mRNA)IBA 08/2019 - 01/2018
2	LigandsIBA 01/2017 - 01/2017
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2017 - 03/2012
2	orteronelIBA 03/2015 - 03/2015
2	Amylases FDA Link 03/2015 - 03/2015
2	danusertibIBA 01/2013 - 03/2012
2	Bleomycin (Blenoxane)FDA LinkGeneric 03/2012 - 03/2003
2	Dexamethasone (Maxidex)FDA LinkGeneric 06/2011 - 02/2007
2	Hemoglobins (Hemoglobin)IBA 01/2010 - 11/2007
1	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 12/2023
1	Deoxyribonucleases (DNase)FDA Link 12/2023
1	Cyclin-Dependent Kinase Inhibitor p21IBA 11/2023
1	Colony-Stimulating Factors (Colony Stimulating Factor)IBA 11/2023
1	lenvatinibIBA 09/2023
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2023
1	AntigensIBA 01/2023
1	Radium-223IBA 01/2023
1	Opioid Analgesics (Opioids)IBA 01/2022
1	Monoclonal AntibodiesIBA 01/2022
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2021

Therapy/Procedure

70	Castration 12/2023 - 09/2009
54	Drug Therapy (Chemotherapy) 12/2023 - 02/2003
35	Therapeutics 03/2024 - 02/2003
7	Radiotherapy 01/2022 - 08/2005
5	Cystectomy 05/2024 - 01/2015
2	Aftercare (After-Treatment) 01/2018 - 01/2010
1	Combined Modality Therapy 11/2023
1	Orthopedic Procedures 01/2022